Imaging Findings of Granular Cell Tumor of the Breast with Virtual Touch Tissue Imaging Quantification Correlation

Volume 4, Issue 5, October 2019     |     PP. 176-185      |     PDF (527 K)    |     Pub. Date: September 24, 2019
DOI:    255 Downloads     5426 Views  

Author(s)

Cristina Roque Ferreira, Department of Radiology, University Centre Hospitals of Coimbra (CHUC), Portugal
Pedro Gil Oliveira, Department of Radiology, University Centre Hospitals of Coimbra (CHUC), Portugal
Manuel Cruz, Department of Radiology, University Centre Hospitals of Coimbra (CHUC), Portugal
Manuela Gonçalo, Department of Radiology, University Centre Hospitals of Coimbra (CHUC), Portugal
Paulo Donato, Department of Radiology, University Centre Hospitals of Coimbra (CHUC), Portugal

Abstract
In our institution, two cases of granular cell tumor of the breast described in this document were observed. Both share a similar clinical-radiological aspect, very similar to a carcinoma; so, in both cases, the VTIQ study was carried out. In one of the cases, after VTIQ study, the characteristics of malignancy were reinforced, however, the other presented characteristics that diminished its suspect. This difference in behavior can be explained by peculiarities in the histopathological characteristics. Despite the small number of cases, this study may show that the VTIQ was not enough to reduce the suspicion of malignancy in these lesions, with only the biopsy of the lesions remaining the only reliable diagnostic method.

Keywords
Granular Cell Tumor; Tumor Breast; Oncology diagnosis; Innovation; Virtual Touch Tissue Imaging Quantification (VTIQ)

Cite this paper
Cristina Roque Ferreira, Pedro Gil Oliveira, Manuel Cruz, Manuela Gonçalo, Paulo Donato, Imaging Findings of Granular Cell Tumor of the Breast with Virtual Touch Tissue Imaging Quantification Correlation , SCIREA Journal of Clinical Medicine. Volume 4, Issue 5, October 2019 | PP. 176-185.

References

[ 1 ] Corso G, Di Nubila B, Ciccia A, et al. Granular cell tumor of the breast: Molecular pathology and clinical management, The Breast Journal 2018;1–5. DOI: 10.1111/tbj.13036
[ 2 ] Lara MC, Herrera AM, Cardoso RT, López DL. Granular cell tumor in breast: a case report Breast Cancer - Targets and Therapy, 2017:9 245–248 DOI: 10.2147/BCTT.S131446
[ 3 ] Fujiwara K, Maeda I, Mimura H. Granular cell tumor of the breast mimicking malignancy: a case report with a literature review, Acta Radiol Open. 2018 Dec; 7(12): 2058460118816537. DOI: 10.1177/2058460118816537
[ 4 ] Yang WT, Edeiken-Monroe B, Sneige N, Fornage BD. Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound, 2006, 34: 153-160. https://doi.org/10.1002/jcu.20227
[ 5 ] Adeniran A, Al-Ahmadie H, Mahoney MC, Robinson-Smith TM. Granular cell tumor of the breast: a series of 17 cases and review of the literature. Breast J, 2004, 10: 528-531. DOI:10.1111/j.1075-122X.2004.21525.x
[ 6 ] Jia-Wei Sun, Xiao-Lei Wang, Qing Zhao, et al. Virtual touch tissue imaging and quantification (VTIQ) in the evaluation of breast lesions: The associated factors leading to misdiagnosis. European Journal of Radiology 110 (2019) 97–104 DOI: https://doi.org/10.1016/j.ejrad.2018.11.021
[ 7 ] Frey, H. Realtime elastography. A new ultrasound procedure for the reconstruction of tissue elasticity. Radiologe, 2003. 43(10): p. 850-5. DOI:10.1007/s00117-003-0943-2
[ 8 ] Michael Golatta. Evaluation of Virtual Touch Tissue Imaging Quantification (VTIQ - 2D-SWE) in the Assessment of BI-RADS® 3 and 4 lesions: Can patient selection for biopsy be improved? – A confirmatory Multi-Center-Study, by Siemens Medical Solutions Application, Dec. 2015 - Out 2017.https://clinicaltrials.gov/ct2/show/NCT02638935
[ 9 ] J. Huyskens, C. Geniets. Granular Cell Tumor in the Breast Mimicking Breast Carcinoma, JBR–BTR, 2014, 97: 289-290. DOI: http://doi.org/10.5334/jbr-btr.1331
[ 10 ] Althausen AM, Kowalski DP, Ludwig ME, Curry SL, Greene JF. Granular cell tumors: a new clinically important histologic finding. Gynecol Oncol. 2000;77:310-313.